Research to Understand and Prevent Exacerbations in Cystic Fibrosis Extended Data 5 6 Patient information sheets 1 ICF 2 Group A, Group B, and Healthy volunteer PIS CFRSD-CRISS and additional questions, CFQ-R, eQ5d-5l, PSQI, Home environment questionnaire Study questionnaires 3 Patient instruction sheets Spirometry, saliva, dried blood spot, nasopharyngeal swab, study chest instructions, study app instructions Frequently asked questions 4 Group A, Group B, and Healthy Volunteer ICF SPIRIT checklist actigraphy, home pollution monitors, study app spirit checklist